Pharmacokinetics, pharmacodynamics and safety of 15 mg-tolvaptan administered orally for 7 consecutive days to Chinese patients with child-Pugh B cirrhosis

Background: Tolvaptan, a selective vasopressin V2-receptor antagonist, can elicit a diuretic effect without significant electrolyte loss.The aims were to evaluate multiple-dose pharmacokinetics, pharmacodynamics and safety of daily administration of 15 mg tolvaptan in Chinese adult patients with confirmed Child-Pugh Class B cirrhosis accompanied by

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The effect of liquidity, profitability, sales growth, and dividend policy on stock prices after the implementation of IFRS

The objective of this research is to find out the effect of liquidity (CR), profitability (ROA), sales growth (SG), and dividend policy (DPR) on the stock APP CONTROLLED price after the implementation of IFRS.This is a quantitative research with the samples consisting of 13 companies of the 45 companies listed on LQ45 in Indonesia Stock Exchange (I

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